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There aren’t many frontiers left in the world. Explorers have scaled the world’s tallest mountains and taken samples from Antarctica’s deepest subglacial lakes. You can even visit remote locales from your web browser. And yet, some corners of the Earth still remain essentially uncharted by Western travelers. Here are some of the coolest underexplored places around the globe.

This region, home to at least 14 of the Amazon’s uncontacted tribes, is one of the most isolated places in the world, in part by design. An estimated 2000 indigenous people live autonomously from the Brazilian government in an area about the size of Austria. The tribes’ right to live in isolation is protected by a federal agency charged with preventing outsiders from invading indigenous territories.

Home to temperate rainforests, glaciers, fjords, and hot springs, northern Patagonia is one of Chile’s wildest landscapes. It’s the country’s most sparsely populated region and has only been accessible by highway since the ‘80s. The Northern Patagonian Ice Field remains one of the largest masses of ice outside the polar regions.

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